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General Surgery

The Acute Abdomen

A physiology-first approach to undifferentiated abdominal pain for MRCS and early surgical assessment.

14 min readUpdated 10 August 2026
Begin lesson

Key points before the detail

  1. 01

    Start with physiology and time-critical syndromes before naming a disease.

  2. 02

    Give analgesia early; appropriate analgesia does not prevent accurate assessment.

  3. 03

    Pain mechanism and migration often carry more information than a pain adjective alone.

  4. 04

    Choose imaging to answer a specific question: perfusion, perforation, obstruction, bleeding, biliary or pelvic pathology.

  5. 05

    A normal early lactate, white-cell count or CRP does not exclude serious intra-abdominal pathology.

SurgAtlas illustration comparing visceral, parietal and referred abdominal pain, including pain localisation and migration patterns relevant to the acute abdomen.
Visceral, parietal and referred pain mechanisms help explain localisation, peritoneal irritation and migration in the acute abdomen.Illustration: SurgAtlas
Section 01

1. Ask the dangerous question first

Undifferentiated abdominal pain is a syndrome, not a diagnosis. Before constructing a long differential, identify whether the patient has shock, generalised peritonism, bowel ischaemia, perforation, strangulation, uncontrolled bleeding or sepsis. These findings determine urgency and often change the order of investigation and treatment.

Diagnosis and resuscitation should proceed together. A deteriorating patient should not wait for diagnostic certainty before senior surgical, anaesthetic or critical-care involvement.

Section 02

2. Use pain mechanism to organise anatomy

Migration is especially useful because it may reflect changing anatomy. Classic appendicitis begins as vague periumbilical visceral pain and localises to the right iliac fossa as adjacent parietal peritoneum becomes inflamed.

Pain mechanismTypical qualityAnatomical meaning
VisceralDull, poorly localised, often midlineStretch, distension or ischaemia of a viscus; foregut tends to epigastrium, midgut periumbilical region and hindgut lower abdomen.
ParietalSharp, well localised, worse with movement or coughingIrritation of parietal peritoneum; guarding and percussion tenderness may develop.
ReferredPain felt away from the diseased organConvergence of visceral and somatic afferents; for example diaphragmatic irritation may refer to the shoulder.
Section 03

3. The first ten minutes: A–E plus immediate actions

  • Keep nil by mouth until aspiration risk and need for urgent procedure are clear.
  • Give analgesia and antiemetics early, then reassess.
  • Give prompt antibiotics when intra-abdominal sepsis, perforation, cholangitis or another bacterial emergency is suspected, following local antimicrobial policy.
  • Escalate early for instability, peritonism, suspected ischaemia/strangulation, free perforation, uncontrolled bleeding or high-risk diagnostic uncertainty.
StepKey actions
AirwayConfirm patency; seek early anaesthetic help if consciousness is reduced or major haematemesis threatens airway protection.
BreathingRespiratory rate, oxygen saturation and chest examination; remember thoracic disease can present as abdominal pain.
CirculationPulse, blood pressure, capillary refill and perfusion; IV access, bloods and reassessed fluid resuscitation when hypovolaemic.
DisabilityMental state, glucose and early analgesia.
ExposureInspect the abdomen, groins, scars, stomas, back and skin while preserving dignity and temperature.
Section 04

4. History and examination that change probability

  • Pain: site, migration, onset, tempo, colicky versus constant character, radiation, provoking factors and trajectory.
  • Associated symptoms: vomiting, last stool/flatus, diarrhoea or bleeding, urinary symptoms, pregnancy possibility and gynaecological symptoms, fever, rigors and syncope.
  • Background: previous abdominal or bariatric surgery, known hernia, gallstones, IBD, ulcer disease, malignancy, vascular disease and medication such as NSAIDs, steroids, antithrombotics or opioids.
  • Examination: look before touching, palpate gently away from pain, assess involuntary guarding/percussion tenderness, examine relevant hernial orifices and complete chest/cardiovascular examination.
  • DRE, pelvic and testicular examinations are selective: perform them when the result answers a clinical question, with consent and a chaperone.
Section 05

5. Red flags that should change your tempo

  • Shock, syncope, active GI bleeding or a rapidly falling haemoglobin.
  • Generalised guarding/rigidity, marked percussion tenderness or evidence of free perforation.
  • Pain out of proportion to examination, metabolic acidosis or embolic/atherosclerotic risk: consider mesenteric ischaemia.
  • Persistent severe pain in obstruction, focal tenderness, fever, tachycardia, rising lactate or a closed-loop CT pattern: consider strangulation/ischaemia.
  • Painful irreducible hernia, skin discolouration or systemic toxicity.
  • Pregnancy with pain, bleeding, syncope or shoulder-tip pain: exclude ectopic pregnancy.
  • Previous bariatric surgery with severe or intermittent unexplained pain: internal hernia can have deceptively mild findings.
  • Immunosuppression or corticosteroid use may blunt fever and peritonism.
Section 06

6. Investigations: ask what the test must answer

InvestigationUse it to answer
BedsidePhysiological trend, glucose, urine findings, cardiac mimics/risk and pregnancy status where relevant.
BloodsAnaemia, inflammation, renal/electrolyte disturbance, hepatobiliary or pancreatic clues, coagulation and perfusion/lactate in the unwell patient.
UltrasoundBiliary disease, pelvic/early pregnancy questions and selected hernias or younger-patient pathways.
CT abdomen/pelvis with IV contrastPerforation, obstruction, diverticulitis, abscess, complicated appendicitis, malignancy and many adult acute-abdomen questions.
CT angiographyMesenteric ischaemia or ongoing major GI bleeding where arterial localisation matters.
CT KUBTypical renal colic when imaging is required; not a generic acute-abdomen scan.
Section 07

7. A five-step MRCS viva structure

This structure keeps an answer safe when the exact diagnosis is uncertain. It also prevents a common viva failure: reciting a differential while ignoring deteriorating physiology.

  • 1. State the dominant syndrome and immediate threats.
  • 2. Give the first resuscitation actions.
  • 3. Name two or three discriminating history/examination findings.
  • 4. Choose the first-line investigation and explain what it must answer.
  • 5. State the escalation threshold and likely source-control route.
ReadingRetrieval

Close the notes and answer these

Try each question from memory before revealing the answer. These public prompts are a small preview of the integrated retrieval system inside SurgAtlas.

01What should be your first question in an undifferentiated acute abdomen?
Answer

Whether the patient is physiologically unstable or has evidence of a time-critical syndrome such as peritonitis, bowel ischaemia, perforation, strangulation, major haemorrhage or sepsis.

02How do visceral and parietal pain differ?
Answer

Visceral pain is typically dull and poorly localised from organ stretch/distension/ischaemia; parietal pain is sharper and well localised because the parietal peritoneum is somatically innervated.

03What abdominal finding should never be omitted when assessing possible obstruction?
Answer

Examination of relevant hernial orifices.

04When is CT angiography particularly useful?
Answer

When mesenteric ischaemia or ongoing major GI bleeding is suspected and arterial perfusion/localisation must be assessed.

05Can a normal early lactate exclude mesenteric ischaemia?
Answer

No. A normal early lactate does not exclude bowel ischaemia; clinical context, imaging and repeated assessment are essential.

References & editorial basis

  1. SurgAtlas production source. General Surgery — The Acute Abdomen, clinical and publication review completed 17 July 2026.
  2. NICE. Related emergency management principles should be applied alongside current condition-specific NICE guidance and local pathways; this lesson is educational and not a substitute for local acute-care protocols. Source ↗

This lesson is derived from the corresponding SurgAtlas production teaching material. Where the source makes current management or guideline claims, the public lesson uses the cited contemporary guidance. It is written for education and examination preparation, not as patient-specific clinical advice.

Editorial details
Author & editorDr. Ali Heidari

Medical Doctor (MD) · MRCS Part A · Physician · Surgical Educator

Published 10 August 2026Updated 10 August 2026
Clinical use

SurgAtlas is an educational resource. For patient care, verify current national guidance, local antimicrobial and transfusion policies, specialty pathways and individual patient factors.

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