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General Surgery

Acute Appendicitis

Move from migratory pain to probability-based imaging and source control.

14 min readUpdated 10 August 2026
Begin lesson

Key points before the detail

  1. 01

    The appendiceal base is found where the three taeniae coli converge.

  2. 02

    Classic pain migrates from central abdomen to the right iliac fossa.

  3. 03

    Imaging strategy depends on probability, age and pregnancy.

  4. 04

    Laparoscopic appendicectomy is standard for most patients.

  5. 05

    Antibiotics-first treatment is selective and recurrence-aware.

Section 01

1. Definition and mechanism

Luminal obstruction, lymphoid hyperplasia or faecolith-related stasis can raise intraluminal pressure, impair venous/lymphatic drainage and allow bacterial invasion. Clinical course is variable, so do not use a rigid time-to-perforation model.

Section 02

2. Anatomy explains atypical symptoms

Appendix positionClinical consequence
PelvicSuprapubic pain, urinary frequency or diarrhoea.
Retrocaecal/retrocolicFlank or back pain, less anterior peritonism, possible psoas sign.
Pre-/post-ilealCentral pain, vomiting or diarrhoea.
BasePosteromedial caecum where the three taeniae coli converge.
Section 03

3. Presentation and differential

  • Visceral T10 pain often starts centrally then localises to the RIF when parietal peritoneum inflames.
  • Anorexia, nausea and low-grade fever are common; vomiting usually follows pain.
  • RIF tenderness, guarding and pain on coughing raise probability but are not individually diagnostic.
  • Older, pregnant and immunosuppressed patients may have muted or atypical signs.
Section 04

4. Probability and imaging

  • Use scoring systems as adjuncts, not replacements for judgement.
  • A non-visualised appendix on imaging is not automatically normal; interpret secondary signs and clinical probability.
Patient groupPreferred approach
Clinically well, low probabilityConsider observation/reassessment or discharge only with clear safety-netting.
Intermediate probability adultCross-sectional imaging; CT is common in non-pregnant adults.
Child/young personUltrasound first where expertise is available; MRI/justified CT if non-diagnostic.
PregnancyUltrasound first, then MRI when non-diagnostic.
Section 05

5. Uncomplicated appendicitis

  • Laparoscopic appendicectomy is the standard operative approach for most patients.
  • Give pre-operative broad-spectrum antibiotics according to local policy.
  • Routine postoperative antibiotics are not needed after uncomplicated disease with adequate source control.
  • Identify the appendix by following the taeniae coli and send the specimen for histopathology.
Section 06

6. Antibiotics-first treatment is selective

Imaging-confirmed uncomplicated appendicitis can be treated non-operatively in selected patients, but recurrence and later appendicectomy remain possible.

  • Exclude diffuse peritonitis, uncontrolled sepsis, abscess and suspected tumour.
  • An appendicolith increases failure/complication risk and often favours appendicectomy.
  • Ensure reliable follow-up and explain recurrence/readmission risk.
Section 07

7. Complicated appendicitis

ScenarioManagement principle
Free perforation/generalised peritonitisResuscitation and urgent operative source control.
Stable localised abscess/phlegmonAntibiotics, observation and image-guided drainage when appropriate; early laparoscopy is an expert alternative.
Failure of conservative careReassess and proceed to drainage or surgery.
Older adult or suspicious imagingAssess for appendiceal/caecal neoplasm after recovery.
ReadingRetrieval

Close the notes and answer these

Try each question from memory before revealing the answer. These public prompts are a small preview of the integrated retrieval system inside SurgAtlas.

01Where is the appendiceal base found?
Answer

On the posteromedial caecum where the three taeniae coli converge.

02Why does appendicitis pain migrate?
Answer

Early visceral afferent pain is poorly localised centrally; later parietal peritoneal inflammation localises pain to the RIF.

03What is the usual first imaging test in pregnancy?
Answer

Ultrasound, followed by MRI if non-diagnostic.

04What is the standard operation for most appendicitis?
Answer

Laparoscopic appendicectomy.

05What feature makes antibiotics-first management less attractive?
Answer

An appendicolith, because it is associated with higher failure/complication risk.

References & editorial basis

  1. SurgAtlas production source. General Surgery — Acute Appendicitis. Public lesson curated from the corresponding production chapter.
  2. WSES Jerusalem Guidelines. Diagnosis and treatment of acute appendicitis — 2025 edition published 2026, as recorded in the SurgAtlas source register.

This lesson is derived from the corresponding SurgAtlas production teaching material. Where the source makes current management or guideline claims, the public lesson uses the cited contemporary guidance. It is written for education and examination preparation, not as patient-specific clinical advice.

Editorial details
Author & editorDr. Ali Heidari

Medical Doctor (MD) · MRCS Part A · Physician · Surgical Educator

Published 10 August 2026Updated 10 August 2026
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SurgAtlas is an educational resource. For patient care, verify current national guidance, local antimicrobial and transfusion policies, specialty pathways and individual patient factors.

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